PREDROL

DOSAGE AND ADMINISTRATION:

Methylprednisolone Tablets are indicated in the following conditions:

1. Endocrine Disorders.

Primary or secondary adrenocortical insufficiency (hydrocortisone or cortisone is the first choice, Synthetic analogs may be used in conjunction with mineralocorticoids where applicable, In infancy mineralocorticoid supplementation is of particular importance).

• Congenital adrenal hyperplasia
• Nonsuppurative thyroiditis
• Hypercalcemia associated with cancer.

2. Rheumatic Disorders.

As adjunctive therapy for short-term administration (to tide the patient over an acute episode or exacerbation) in:

• Rheumatoid arthritis, including juvenile rheumatoid arthritis (selected cases may require low dose maintenance therapy)
• Ankylosing spondylitis
• Acute and subacute bursitis
• Synovitis of osteoarthritis
• Acute nonspecific tenosynovitis
• Post-traumatic osteoarthritis
• Psoriatic arthritis
• Epicondylitis
• Acute gouty arthritis

3. Collagen Diseases

During an exacerbation or as maintenance therapy in selected cases of:During an exacerbation or as maintenance therapy in selected cases of:

• Systemic lupus erythematosus
• Systemic dermatomyositis (polymyositis)
• Acute rheumatic carditis

4. Dermatologic Diseases.

• Bullous dermatitis herpetiformis
• Severe erythema multiforme (Stevens-Johnson syndrome)
• Severe seborrheic dermatitis
• Exfoliative dermatitis
• Mycosis fungoides
• Pemphigus
• Severe psoriasis

5. Allergic States.

Control of severe or incapacitating allergic conditions intractable to adequate trials of conventional treatment:

• Seasonal or perennial allergic rhinitis
• Drug hypersensitivity reactions
• Serum sickness
• Contact dermatitis
• Bronchial asthma
• Atopic dermatitis

6. Ophthalmic Diseases

Severe acute and chronic allergic and inflammatory processes involving the eye and its adnexa such as:

• Allergic corneal marginal ulcers
• Herpes zoster ophthalmicus
• Anterior segment inflammation
• Diffuse posterior uveitis and choroiditis
• Sympathetic ophthalmia
• Keratitis
• Optic neuritis
• Allergic conjunctivitis
• Chorioretinitis
• Iritis and iridocyclitis

7. Respiratory Diseases

• Symptomatic sarcoidosis
• Berylliosis
• Loeffler’s syndrome not manageable by other means

Fulminating or disseminated pulmonary tuberculosis when used concurrently with appropriate antituberculous chemotherapy Aspiration pneumonitis

8. Hematologic Disorders

• Idiopathic thrombocytopenic purpura in adults
• Secondary thrombocytopenia in adults
• Acquired (autoimmune) hemolytic anemia
• Erythroblastopenia (RBC anemia)
• Congenital (erythroid) hypoplastic anemia

9. Neoplastic Diseases

• Leukemias and Iymphomas in adults
• Acute leukemia of childhood

10. Edematous States

To induce diuresis or remission of proteinuria in the nephrotic syndrome, without uremia, of the idiopathic type or that due to lupus erythematosus.

11. Gastrointestinal Diseases

To tide the patient over a critical period of the disease in:

• Ulcerative colitis
• Regional enteritis

12. Nervous System

• Acute exacerbations of multiple sclerosis

13. Miscellaneous

Tuberculous meningitis with subarachnoid block or impending block when used concurrently with appropriate antituberculous chemotherapy.

• Trichinosis with neurologic or myocardial involvement.